As there are very few roundabouts in the USA, we have either traffic signals (lights) or Stop signs. Sometimes there is a Stop sign for only the cross street and sometimes there are 4-way Stop signs. If you encounter a Stop sign then...stop. Stop completely. No, really, stop, I'm not kidding. The police are quite insistent on enforcing that law! Once you are stopped determine if the cross traffic also has to stop. There is usually a small sign below the stop sign that will say 4-Way if it is an intersection where cars driving in all directions must stop.
If it is not a 4-way stop, wait until there is sufficient time and space for you to cross (well, duh)or turn if you are turning onto that street.
If it is a 4 way stop then you get to participate in what I think of as a little car ballet. The first car to have arrived at the intersection goes first. Second foes second and so forth. Even if there is a line (queue) of cars waiting to get to the stop sign each car must stop in turn as they reach the sign.
In the unlikely even that two cars arrive at the intersection at precisely the same time the car on the right has the right of way, or gets to go first. In any situation at a 4 way stop the best policy is to start slowly and keep a watchful eye for anyone who is breaking the protocol.
Don't get too overwrought over this explanation. It sounds more complicated than it really is.
The hardest thing you will have to get used to will be driving from the left side of the car rather than the right. But that helps you remember that you need to keep to the right rather than the left.
Have a great time here in Florida. And spend lots of money! LOL We need it.
Joe
Tampa FL