If you want central you can't get much better then the Bellagio, along with its luxurious pool grounds, great restaurants the Hotel is a class act. The Std rooms are a bit smaller then those od the Wynn and Palazzo.
Book a Lake view Fountain room and you will be very happy..
The Wynn is also a tremendous Hotel with great pool grounds that are shared with its sister hotel the Encore. The Wynn has some of the finest restaurants in town along with larger Std rooms. The Wynn and Encore are located a bit North on the strip. The Wynn is IMO the class of the strip.
The Palazzo, beautiful hotel closer to mid strip, great Std rooms, class act Hotel with some great restaurants. The Palazzo shares the upper level of the Venetian with its sister Hotel, Palazzo pools grounds are not as nice IMO as those of the Wynn and Bellagio but still a high end class Hotel.
Each Hotel has its pros and cons but each one will satisfy your needs..
If you look at this picture you will see in the background two buidings the same in shape, those are the Encore on the left and the Wynn on the right. Next to the Wynn, on the right again you see the Palazzo. This picture was taken from the Mirage with is North of the center strip Bellagio.
http://s696.photobucket.com/albums/vv323/TheDiceman7/?action=view¤t=DSC00073.jpg
The Wynn
http://s696.photobucket.com/albums/vv323/TheDiceman7/?action=view¤t=DSC00060.jpg
The Palazzo
http://s696.photobucket.com/albums/vv323/TheDiceman7/?action=view¤t=DSC00077.jpg
The Bellagio
http://s696.photobucket.com/albums/vv323/TheDiceman7/?action=view¤t=DSC00110.jpg
http://s696.photobucket.com/albums/vv323/TheDiceman7/?action=view¤t=DSC00125.jpg