My husband and I just came back from a 3-night stay in Venice and we found the Residenza alle Zattere a fabulous place to stay. Francesco the owner was courteous and helpful and gave us lots of tips about where to eat and interesting places to visit. (And in contrast to an earlier reviewer - while we were there a guest who had lost luggage in transit was overjoyed with the help Francesco offered to help her recover it!)
The room we had was small - but with a huge bathroom and a little sitting room too - so overall it suited us very well. The breakfast was simple - yoghourt and muesli, croissant and bread rolls - and as much good coffee as we could drink!. The room, bathroom and breakfast area were all clean and well maintained.
But its the location that makes a stay here really special. As other reviewers have mentioned you are just 5 minutes from the quayside walk of the Zattere in one direction - and about 10 minutes from the Grand canal in the other direction. The small sqaure thats about 5 minutes walk has several good restaurants and a great ice cream parlour.
We woud highly recommend the Residenza alle Zattere to anyone looking for a quiet, clean, wonderfully located B and B with a host who knows and loves his city and will do his best to make your stay memorable.