We stayed in this hotel for 2 nights at the end of March.

It is in a great location for exploring Pisa. It was less than a five minute walk to the leaning Tower and the surrounding attractions. It was a 10euro cab ride from the airport but we easily walked to the train station and it took no more than 10 minutes.

The hotel is very clean and the rooms were plenty big enough. The only problem was the size of the bathroom. There was no bath and the shower was a corner shower that was quite cosy.
The front desk staff are very friendly, and the hotel seems to be family run.

Overall I would recommend staying in the hotel for the location.

Great location. Good room. Nice, simple breakfast in a well-decorated place. No English language TV that we could find, though we were pretty tired from walking around.

We would have stayed another day at the end of our trip, but they wouldn't/couldn't print an airplane boarding pass for us, so we chose a different hotel that would. Highly variable English skills at desk, but between their weak English and my even weaker Italian, we did just fine. Would stay there again.

Also, we just enjoyed Pisa far more than we expected we would.

On the strength of reviews on TripAdvisor I booked 3 rooms at this hotel and was not disappointed. Although not particuarly cheap at 140 euros per room per night the rooms were spacious and spotlessly clean. Bathrooms chic and modern with excellent shower and soap etc provided. The staff were helpful and spoke some English. Although the rate did not include breakfast we were given free breakfasts both days which were fine - cornflakes, juice, croissants, bread rolls, ham and cheese, cakes and good coffee. Tea was the usual hot water and weak teabags. The hotel was perfectly situated for visiting Pisa and would also thoroughly recommend Osteria Dei Cavalieri for excellent food at a reasonable price. For lunch went to Black Bar, again cheap and good. Both restaurants within few minutes walk of hotel. Went to Florence by train - one hour and about 10 euros. I would definitely stay here again.

My wife and I spent seven nights in Hotel Novecento, in the first week of January 2008. We wholeheartedly recommend this hotel. The location is perfect - five minutes walk to Campo dei Miracoli with the Duomo, the Camposanto and the Leaning Tower with the advantage of being in a quiet street. And also quite near the Arno river with other attractions, including the Church of Santa Maria della Spina and the impressive Museum of San Matteo. The staff couldn't possibly be friendlier - having stood seven nights we had plenty of occasions to judge. Our room was very comfortable although not particularly spacious, breakfast was delicious. If I have a minor observation to make is that I felt the lack of a proper space for soap and shampoo at the shower. However and contrary to the experience of one reviewer, our room was amply provided with soap and shampoo. The price (125 euros with breakfast) was fair considering all the hotel offers. I also recommend nearby Osteria dei Mille, owned by the son of the hotel proprietary - excellent food, very good price - we actually dined there three times and also had ample opportunity to compare with other restaurants in town.
In short, I don't hesitate in recommending this hotel and will always have the best possible recollection of the friendly staff.