The meaning of "Grand Case" comes from Creole for "big house". This is because this area was originally a home to large wooden houses, cotton plantations and salt ponds and fisherman. The Europeans constantly coming in and out of this area for these commercial regions lent great influence to its culinary world. It was the culinary delights that drew attention to Grand Case and thus its most recent tourist development.

The old wooden houses have since been renovated as Grand Case has gained luxury status, but the charm has forever remained. The architecture of Grand Case is one of the best offerings on the island, and perhaps even one of the most charming in the Caribbean. Houses here are done in "gingerbread style" with a lot of ornamentation. The colors come from a calming palette of pastels that blends in with the backdrop of the island, yet is bright enough to call humble attention upon them as individuals.

Creole style, reminiscent to the famous architectural design in New Orleans, rings in the design of many of the buildings in Grand Case. French flair comes through in the cafes and bistros that Grand Case is known so well for but overall, the Caribbean flavor brings color and pizzazz to the city.