If you are staying in Prague for a few days here's some ideas of places to go, where to eat and where to drink.

Get the 3 day Prague Card - The card gives free transport on the well-connected metro and free entry/discount to most attractions.

Taxis are reasonably priced.  Just remember to agree on a price before getting into the taxi.  

The Old town square (Staromestske Namesti) is a great place to see first. There are places to sit outside in the square itself and have a drink .  If it's a chilly evening they provide heaters to keep you warm. 

In the square you will find the Church of Lady Before Tyn (a fantastic building), The Powder Tower, and the Old Town Hall Tower & Astronomical Clock.  Try to be in the square just before the hour and join the crowd to watch the clock.  For a small fee you can go up to the top of The Town Hall and enjoy the views of Prague's old town.

Another way of seeing Prague's old town is from the roof terrace of the U Prince anyone can go into the hotel walk towards the back you will see the lift which will take you to the roof terrace there you can enjoy a very nice meal or just enjoy a drink and take in the fantastic views of Prague.

Charles Bridge (Karlův most) is a must.  Try to get there early though to avoid the crowds. Half way across the bridge on the right hand side (if walking towards the castle) there is an image which is highly polished.  The reason for this people say it is good luck to touch the image of the saint, so this sometimes draws a crowd. As of now, June 2009, part of the bridge is under renovation and partially covered.

Petrin Hill with its tower is also worth a visit.  You will find the funicular railway on Ujezd (before you go to the station look out for the statues on the steps. The statues are of people and commemorates communism but not in a good way. The statues show how communism destroys people) The funicular takes you to the top of the hill, open from 9.00 till 23.30, if you don't fancy the walk. There is a small charge you can buy your ticket from a machine before you go through to the funicular itself or at the kiosk if you have no change. There are three stops on the way so if you did fancy a little walk up you could hop off at one of these. Petrin Tower provides fab views of Prague so don't forget your camera. Just inside the Tower you will find a small cafe serving snacks and drinks. There is a small charge to go up the tower - open from 10.00 till 17.00 in winter 22.00 in the summer. You can purchase your ticket from the kiosk just inside the tower.  There is also an observatory on Petrin Hill near the rose gardens where you can go to on an evening, a notice on the door will tell you when it is open depending on the weather, for a small charge you can visit the observatory. The guide will show you the  two telescopes and you will have the chance to observe the sky for stars and galaxies. Well worth a visit on an evening although I would advise you to wrap up warm if visiting in the winter months as it can get very cold in there.

Bohemia Bagel is worth a visit for lunch or a quick snack serves great soup and bagels of course. This is on Ujezd over the road from the furnicular station. 

The Castle is worth a visit and in the grounds you will find Golden Lane orignally called Zlatnicka Ulicka (Goldsmith's Lane).  The reason for its name is that goldsmiths used to reside here. You will be charged a small fee to walk down the lane - the small houses are shops which you can browse around....mind your head as you walk in!

U Sadlu restaurant  Klimentska 2 great looking restaurant serves Czech food and beer but sadly not for vegetarians! Mentioned this restaurant as there is a cafe bar, at the end of this road on the corner near U Sadlu, nice bar with very reasonably priced drinks.  Enjoy  beers and cocktails here.   

U Medviku beer Hall Na Pertyne 7 is a great place to try the czech beers and have something to eat here. 

Right by the beer Hall there is a wine merchant called  Monarch  15 Na Perstyne - fantastic wine served by the glass or bottle and if feeling a little hungry why not have a fondue here too.    

Wenceslas Square (Vaclavske Namesti) which is actually a road has loads of shops , casinos, restaurants and clubs with dancing girls and The Grand Hotel Europa where you can pop in for a coffee. 

Cafe Radost FX restaurant offers vegetarian food open 11am to 4.00am at Bělehradská  120 Prague 2.

Red Hot & Blues tex mex restaurant and winter garden open 9.00 - 23.00 on Jakubská 12 near to the Old Town great food and has live Jazz music played here in the evenings.

Cantina another mexican restaurant on the other side of the river Mala Strana Ujezd 38 serves great food and jugs of margaritas.

Bar Bar just off Ujezd Všehrdova 12-24 serves food and great hot very alcoholic drinks!  12.00 - 24.00 week days and  till 2 am on Friday and Saturday.

U zavesenyho Kafe short walk from the Castle at Uvoz 6 stop to have a nice beer and some food here. open from 11.00 to 23.00. Walking back down this road you will come across a very nice looking restaurant called Cowboy's steak and cocktails number 40 but don't worry if you don't eat steak, vegetarian food is also available.

Not far from the old town square is a great rock bar/night club called Harley's Bar. Enjoy the music and cocktails here Dlouhá 18 open from 4 till very late!.

Also in the Old Town is an Irish bar called Molly Malone's U Obecniho Dvora 4. It's full of charm & character. Open till 1am

A good way of seeing Prague in a short space of time, if you are short of time to walk around, is to try a vintage car tour.  You will see the cars in the Old Town square. An english speaking guide takes you around Prague to all the main attractions.