Bradley International Airport, Connecticut’s only airport with national commercial traffic, is just north of Hartford, which is about 60mi (100km) away. It has connections to many major U.S. cities (though there are significantly fewer connections to destinations west of the Rockies) and a few Canadian ones (mainly Montreal and Toronto) via most of the main airline companies. The T.F. Green Airport of Providence, Rhode Island offers essentially the same destinations, but is about 10 or 15mi (16 to 24km) closer than Bradley. Unless you are flying in from a major city like Los Angeles or Philadelphia, you will probably need to transfer planes in (or drive up from) New York to get to either of these. You could also take a charter flight to one of the smaller regional airports in the area, such as Groton/New London or Westerly.

A taxi from either airport would be fairly expensive, so consider renting a car. There are offices for all the major rental agencies at both airports. Interstate 95 connects Providence to Mystic; take I-95 going south. From Hartford, take Rt. 2 east to I-395 south to I-95 north.

If you are already in Connecticut and want to arrive in a slightly more unique fashion, rent a boat or yacht and pull up in Mystic Seaport. Reservations for docking spaces are required, and the museum requests that guests arrive after 12:40pm and leave before 12:40pm, as the channel leading to Mystic Seaport is fairly narrow and there are shoals on either side.