Something would truly be amiss if a visitor failed to partake in at least one of two of Key Largo's most notable activities, scuba diving and sport fishing. Many call Key Largo the diving capital of the world, and whether it is number one or not, it still should not be missed. Key Largo's coral reefs are so extensive and varied that remaining on land causes one to miss a great deal of what makes Key Largo stand out from any other Florida destination. An interesting reef to check out is Spiegel Grove, on the Atlantic side of the Keys, where an artifical reef was created in 2002 by intentionally sinking a 510 foot retired Navy ship. Another diving place to consider for those of varying experience levels is Molasses Reef, which extends three feet above the surface at some points and then dips more than 55 feet below. For avid and novice fishers, there are plenty of opportunities to charter a private sport-fishing boat or jump aboard a "party boat" for nighttime fishing excursions. As Key Largo attracts some of the world's best boat captains, investing in a boat charter at least once can be a memorable experience.

Key Largo rests between two bodies of water, the Atlantic where the reefs are located and the shallow waters of Florida Bay. This is where the islands of Everglades National Park harbor the homes of birds, dolphins, manattees and other wildlife. Visitors should take an enviro-tour or kayak tour into this pristine wilderness area. There are a few high quality Dolphin swim programs also offered on the island.

Other popular watersports offered in the area include kayaking or Hobie Cat sailing. Lessons for which can be acquired for an hour up to a whole day. Other activities include jetskis-waverunners and parasailing on the Bay. Sandy beachs are rare in the Keys, but some private ones are available at some of the bayside motels and resorts.