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Your one-stop shop for finding the best flights from San Francisco to Mayaguez. Simply tell us where and when you want to travel and we'll do all the legwork for you. Featuring the most powerful shopping tools on the web, we search the largest online travel websites, established airfare discounters, plus the world's leading airlines and low-cost carriers to bring back thousands of flight options.

Travel information for San Francisco, CA to Mayaguez

Route information
  • San Francisco, CA is 3570 miles from Mayaguez
  • Los Angeles, CA - Los Angeles International Airport is the most popular connection for one stop flights between San Francisco, CA and Mayaguez
Arrival information
  • Eugenio M. De Hostos Airport (Mayaguez, Puerto Rico)
    • Right now, 3 airlines operate out of Eugenio M. De Hostos Airport.
    • Every week, at least 84 domestic flights and 0 international flights depart from Eugenio M. De Hostos Airport.

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