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Your one-stop shop for finding the best flights from Paducah to Des Moines. Simply tell us where and when you want to travel and we'll do all the legwork for you. Featuring the most powerful shopping tools on the web, we search the largest online travel websites, established airfare discounters, plus the world's leading airlines and low-cost carriers to bring back thousands of flight options.

Travel information for Paducah, KY to Des Moines

Route information
  • Paducah, KY is 405 miles from Des Moines
  • Chicago, IL - O'Hare International Airport is the most popular connection for one stop flights between Paducah, KY and Des Moines
Arrival information
  • Des Moines Airport (Des Moines, IA)
    • Right now, 26 airlines operate out of Des Moines Airport.
    • Des Moines Airport offers nonstop flights to 20 cities.
    • Every week, at least 684 domestic flights and 0 international flights depart from Des Moines Airport.

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