Few Hotels in Gananoque Can Match Our Features The Holiday Inn Express Hotel & Suites 1000 Islands - Gananoque, one of the newest Gananoque, Ontario hotels, is situated in the heart of the Thousand Islands. Our hotel's location is just off Hwy 2 and close to Hwy 401. Leisure guests enjoy the convenience of our St. Lawrence River hotel's location, which is close to historic Gananoque and the Gananoque Boat Line. Day trips to Boldt Castle, scenic cruises, sport fishing and Fort Henry are easily accessible from here. You can test your luck at the 1000 Islands OLG Casino, just 0.5 km away from us. Few hotels in Gananoque, Ontario offer corporate guests a better location than we do. We're halfway between Ottawa & Syracuse and Montreal & Toronto. There are three meeting rooms that can handle up to 200 guests, with catering, video conferencing and A/V equipment for the perfect business event. Naturally, there is high-speed Internet access to keep you connect during your stay in the Thousand Islands. Our hotel's upscale amenities will delight every guest. You can start your day with a visit to the free hot breakfast buffet and relax at the end of it in the indoor pool or sauna. The bright and airy Fitness Centre offers a large TV to make workouts fly by. Our rooms feature a microwave and fridge for added value. Our award-winning Gananoque hotel's location and amenities will make your 1000 Islands visit just about perfect.