I will be going to Madrid soon for work - probably staying about 4 nights - and am looking for recommendations for which area to look for hotels. I have been to Madrid before, and I speak passable Spanish, so I don't need to be on the main tourist/visitor track. I will be visiting clients whose offices are on the north end of Madrid, north-east of Chamartin (Avenida de Manoteras), so I am looking for a neighborhood that isn't too far of a commute on the metro and has interesting restaurants and bars and places to walk around in the evenings.
I have stayed in a hotel very close to the offices before, but this area is pretty much just office buildings and residential - not much going on at night. It is easily accesible by public transport, but I had to leave the neighborhood each night to get dinner or even to see anything remotely interesting. I would prefer to stay in a busier area where I can walk or take a quick ride on the metro to get dinner and have a drink or two.
I have also stayed in the Plaza de Santa Ana area, which I really liked. It was great to be able to basically step out of the hotel and have things right there. That was a bit of a commute to get to and from the office each day though since it is basically on the opposite side of Madrid from my clients' offices.
So I'd like to find a happy medium - a neighborhood that has bars and restaurants, people out and about, etc. but is still relatively close to my clients' offices so that I don't have a long commute. Any ideas? Recommendations?