It's our first time in Rome and we want to see and do the usual tourist stuff - Vatican, Colosseum, etc. - but also like to poke around the fun shopping/eating districts & neighborhoods where the locals like to hang (if you're familiar with San Francisco, think Mission, Hayes Valley, Cow Hollow). Where would you recommend we stay in order to maximize both of these experiences? Or should we find the closest hotel to the tourist stuff, since we only have a few days and then we're off to Umbria and Tuscany? We prefer boutique hotels with good customer service, but a decent chain with a skilled concierge is fine, too. We'd like to keep the cost under $250 US if possible. Grazie.