We visited Cesky Krumlov on way from Vienna to Prague and were glad that we spent one night here. The town is a treasure and a wonderful break from all the tourists and crowds. The day we were there was nice and quite and we spend our time walking slowly and visited the castles. We stayed in Castle View Apartments on the top floor and it was extremely quaint and comfortable but I thought if there was fire, it would be a death trap. Anyway, we had dinner across the road, two steps really, and shared our table with another couple. We had a great time and would recommend either a day trip or better still an overnight.
We caught student agency bus to Prague which I would not recommend due to the lack of security with the cases under the bus and their rudness towards passengers. The service is advertised as express but it's not and stops about 6 times on the way to Prague. That is my only complaint.