Well, Sandlake road/Dr Phillips blvd is just west off I4 in the parks/orlando area, and you can find Bonefish grill which is good even if a chain. Jonnie's Hideaway in Crossroads shopping center off exit 68 south of there in Lake Buena vista would be a choice too.
But it will be 7:30+ by the time you get to these areas so I would stop somewhere near there. If you want to save money and those are too pricy for you I would eat late at the beach, or save your seafood eating for when you get to Ormond later in your stay?
I was thinking maybe you might want to sample a different cuisine, because Ybor City is just off I-4 in Tampa. Ybor City is known for its Cuban/Spanish influences.
Check out the Columbia (http://www.columbiarestaurant.com/) which is probably the most famous and well known restaurant in Ybor City.
Do a google search of "restaurants in Ybor City" to see all the options.
There is also a Columbia in Celebration and exit or two before the exit 68 I mentionned.
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