The Orange County Register reported yesterday that WestJet (a low priced Canadian airline) will start to service the John Wayne Airport from both Vancouver and Calgary later this year with daily service, Fares will statrt at $99 each way.
Vancouver service will start on May 2nd, 2011, and Calgary service will start on June 13th. One flight a day and both will use Boeing 737's.
FYI, US Customs will be handled at the Canadian airport, so no need for customs facilities in Santa Ana. (This is common practice, as it is easier and cheaper to staff just a few main Canadian Airports than a much large amount of US Airports that fly to Canada).