I've driven a bit in Turkey and will drive up to Kusadasi and Ephesus when we go again in two weeks.We stay in Altinkum/Didim.
The actual driving part is fine just exercise caution, some of the Turks are speed merchants, best to let them pass when safe to do so.Having said that, out in the countryside the driving is pretty easy and pleasureable.Again, in towns, expect the unexpected!
If you go from Istanbul to Troy, Bergama,Izmir and Ephesus then you will have already covered quite some distance.Turkey is a big country.To undertake a trip east to Pammukale then whilst possible, would curtail how much you actually see and how long you would have in each place,imo.
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