I-70 is closed between Palisade and DeBeque due to the Pine Ridge wildfire. The fire has jumped the CO river and the worry is that it will also jump the interstate. If you are heading east on I-70 out of the Grand Junction area and are stranded (because there really is no easy alternative routes tonight), there are some shelter options. Palisade High School has room for 150 people, including pets. The Riverside Park in Palisade is also available for RVs, campers, tents. There is electricity at that site.
If you are able to afford hotels, Horizon Drive in Grand Junction has the most hotel rooms. Fruita also has hotels off of I-70 and Hwy 50.