I have read many posts and comments lately about the best route to take when driving to PCB, FL. I have been a frequent vacationer to PCB for the last several years and after having driven way too many miles out of the way, we found a clear route that is so much easier than what most of the internet directions give. You can actually access I-65 from most other areas if you can just map your way there, you will not need all those extra exits and turns. The following link will take you to mapquest which gives the simplest directions:
If the link does not work by clicking on it, just copy/paste. I hope this helps those who need more concise directions. Good luck and have a safe trip. We always enjoy our stay there.