MUST DO: Central Park!
and... for what it's worth:
Even with the best itinerary, you will find so much to see and do, you will wind up having to flex your itinerary in my opinion. DO print out a good map of the area you plan to see and study it ahead of time to optimize your "route" of activities. You can spend DAYS just on walking tours of this magnificent city.
DO take your camera EVERYWHERE you go. In 7 days I could take 1000's of pics!
DO take a double decker tour bus- Hop On Hop Off option- It's a great way for a 1st timer to get the lay of the land and sightsee. THIS CAN BE PRE-BOOKED.
DO go to Central Park!- Free! (There is a lot of free stuff in NYC!) But it's HUGE and can take a whole a day or 2 to see the whole thing if you take pics like I do. See Belvedere Castle, Bethesda Terrace, the lakes, skaters, rowers, flora and fauna, and all it offers.
DO go to Top of the Rock in Rockefeller Center. The views are spectacular and offers a great shot of Empire State Building.
DO pre-plan some restaurants, but be flexible to changing that plan....there are over 18,000 places to eat in NYC! I can’t begin to list where all to try.
DO take a look at the “pre-fixe” priced meal options. There are many, and some delicious meals can be had very reasonably in fine restaurants.
I can recommend the NYC Water Taxi, again with the Hop On Hop Off option. You can get a ticket to the World Trade Center Memorial with that ticket.
DO check out the Christmas Window displays at night down 5th Ave and elsewhere if you're going to be there in Dec-Jan, especially the Bergdorf-Goodman windows.
It can be fun to go down to the Good Morning America studio in the morning (EARLY!)... get on TV!!
DO check out some of the churches/cathedrals... St. Patrick's is gorgeous.
There are SO many souvenir shops!!! Shop wisely and compare prices...prices vary quite a bit for the same items.
DO leave room in your suitcase for the gifts!!!
DON'T be afraid of taking the Subway. It's fun, cheap, and a great way to get across town.
DO bring the most comfortable walking shoes you own. Walking is a GREAT way to see the city- the REAL NYC!
DO check out the Market in Grand Central Station. It's awesome. (If you can take dry ice home, get some of their goodies!!)
I THINK the ice skating is free at Bryant Park. (it used to be, but I'm not sure today.) You may have to pay for skate rental.
DO go walk the Brooklyn Bridge. (One of my faves.) It offers a fantastic view of the Manhattan skyline.
Don't forget your phone probably has GPS in it... it can be handy getting around.
Note that prices of nearly everything will be higher in the touristy area of Times Square. Away from there you can get a great pizza lunch, a huge slice and a Coke, for 2 bucks.
I'm sure I've left out a lot, but I hope this helps. I've only been 5 times, but this is what I've discovered on my own. Have a great time!!!