We stayed at the Southwark Premier Inn for 3 days over the Jubilee weekend and found the location to be excellent. You are right in the middle of the "market area" with lots of old traditional London pubs buzzing with activity, restaurants and bistros are also in abundance in this area. There is a tube stop maybe 500 mtrs away... London Bridge, and I`m sure there would have been the normal water transport nearby, but with the Jubilee this was all canceled. The Premier Inn also has a nice olde worlde pub attached to it right on the side of the Thames. Even If your an old wrinkle like me you will enjoy the lively interesting old streets and architecture, and feel safe !!.
All in all a great weekend !!.More