Fantastic time at the Prati! I knew when I booked it that it was close to the Vatican, but even still, I was impressed with its location once we got there. Not only is it close to one of the world's most awe-inspiring places, but it is also in just a nice, normal-feeling Roman neighbourhood. Our room was a fine size (bigger than other comparable ones we've stayed at in Europe), and was well appointed and clean; staff was friendly and helpful.
We'd be happy to stay there again, and in fact, are planning to!