The Locanda Ca’ San Marcuola is about 50 yards from the San Marcuola vaporetto stop. It is in an older building, but inside it was quite modern. We had a 4-person room for the three of us. Our room overlooked the square, where everybody passes by when they get off the vaporetto, talking loudly in the process; how later the hour how louder they talk. We should have asked for a room at the canal side, which would be quieter. Our room was about 10 by 12’ large; the bathroom was around 8’ x 8’, but the shower was small, which seems to be the standard in many of the hotels we have been. The room is otherwise quite comfortable. And as mentioned by others, they have the slowest lift in all of Italy. It was easier to just take the stairs. And their prices are very reasonable considering their location.
Breakfast was continental, but copious and good, with a waitress scurrying around to serve the food. The location is great. There are lots of good restaurants nearby, and the main drag going to the Rialto, to the Piazza San Marco, and the Piazzale Roma is just around the corner. The casino is next door, just in case. They never look crowded, as far as we can ascertain.
Most of the guests take the vaporetto to get to Piazzale Roma, from where they take the No. 5 bus to go to the airport. And vv. There is actually a more convenient way to get to the airport from the hotel. From the hotel you turn right to go to the main drag (turning left will take you to the vaporetto stop) and then turn left (away from the direction to San Marco Square). After walking for a few minutes you will reach the Ponte Guglie bridge, which is a bridge with steps. Don’t go on the bridge but turn right on the Fundamento Pescaria, and 50 yards further you will see the Porta della Guglie boat stop. Total time to get here from the hotel is less than 10 minutes. From there, every half hour, a motorboat stops to take you straight to the airport. This is the Linea Arancio, also called Alilaguna (there are many different water bus companies in Venice) who will charge you €16 for the trip. Or you could buy a ticket ahead of time at a tobacco store for €15. The trip takes about 40 minutes. At the airport quay, the boat will stop at the furthest berth, and signs will tell you that it is a 7 minute walk to the airport. I have seen people huffing and puffing pulling their suitcases, because they don’t want to use the carts to save money. The carts are actually free; you have put in a coin (€0.50, 1, or 2) to unlock the cart, but when you reattach the car to other carts at the end of the trip, you’ll get your money back.
See also: http://www.travelswithhok.com/From_Schladming_to_Venice/Entries/2013/4/24_III__Venice.html
