If you consider staying in this hotel as part of the meeting, conference, business or private trip it is excellent choice. Large size, full of light with excellent sea view rooms, the same high quality of Hilton standards in everything from food to service and accommodation, very convenient location (on the island, far from shocking crowd in the Venice) with very enjoyable 5-10 minutes ride by complimentary shuttle boat to the St. Mark square and back, as many times as you wish, for 7.50 euro per stay, excellent breakfast (fresh squeezed orange juice, fresh squushed carrot with pear juice with hit of ginger, cheeses, smoked salmon, cold cuts and hot dishes), executive lounge, largest venue for conferences in Venice, excellent big spa, rooftop pool (free) with breathtaking view of Venice or you could visit rooftop bar to enjoy sunset.
Venice is extremely overcrowded, we have not seen in whole our life more overcrowded city. When you are coming back to island/to Hilton you looking forward to it, to escape from crowd and relax. Everything in Venice is very expensive. Check prices first and remember about additional charges which might show up on your bill only at the end. There are several restaurants near Hilton hotel and you will enjoy cheeper and not so stressful dining as in the Venice. Within 5 minutes walking distance from the hotel (check map) there is supermarket (Coop), where you could buy almost everything if you need. (Beer two times cheaper that in Canada, wine or prosecco starting from 3 euro, water and coke essentially free compare with Venice).
Venice does not have cars and boat traffic is still reasonable and as result we noticed that quality of the air is excellent, especially at the island where Hilton located.
During happy hours you could sit in the executive lounge next to the window and could see sea water within 10 meters from you, see fishermen, passing boats and enjoys beautiful view of Venice and sunset.
One more comment, about Venice. If you come earlier even 9-10 am or evening it is not very overcrowded. There are no free washrooms in the Italy. Price in public washrooms - 1.50 euro. But if you buy, for example, espresso over counter (not taking seat) it will cost you the same money and you will get key to the washroom. Airport to Hilton hotel by Vaporetto (public water bus) - one and half hour or less, 15 euro, per person. Private boats are available at the same terminal and you could choose right for you. From Hilton Hotel to cruise terminal or train station, by Vaporetto (public water bas) is 15 minutes and cost 7.5 euro per person. Some Vaporetto water bus stops in front of the hotel, other within 5 minutes walking from hotel.
It is simple and very convenient.
Overall, we enjoyed our stay and you will.

Recently stayed as a HH Diamond member, and received an upgrade from a Deluxe Room to Executive with View.

The view from the room was excellent, and the room was a very good size, clean and well kept.

Only concern with the room was the bathroom, which was shower over bath. Unfortunately this meant the shower space was quite small and uncomfortable, especially as the shower head was too low for me. This was a bit disappointing given the space of the room which meant a proper shower could have been included easily.

Turndown service was offered daily, and general service in the hotel was good.

Breakfast buffet in the restaurant was very good, however a cooked to order egg station would have been good. Executive lounge was good, however the location to the side of a bar was a bit awkward - this would have been better placed elsewhere.

Location was on Giudecca, however the hotel runs a shuttle boat for €7.50 per person per stay. Ideally this would be included in the room rate (or even offered for status guest free). Frequency here could be improved - most of the day it was 40 minutes with 2x 1 hour breaks - a day round 20 minute frequency would be good.

Unfortunately the pool closes at the end of September, which was disappointing as the weather was still quite warm in early October. The hotel advertises the pool in the Hilton app, but it is not clear this is only seasonal.

Would definitely return if in Venice in the future.

I would never stay here again. The location is not the best, its far away from everything, so if you like to be isolated and in a quiet area, this should be good, but if you like to walk around and be where the main action is, this place is not for you. Being in Venice the shuttles can be an issue, so I prefer to be on the main land, taxis are crazy expensive!. The rooms are ok, depending on which you get, I had to change mine three times, some are tiny with tiny bathtubs and some are almost double in size with a shower and a bathtub (funny enough all for the same price which is not fair at all!). The rooms are clean and the bed is comfortable, the hotel is full of mosquitos, which is a horrible experience! The breakfast is every, nice bar at the top with a nice view, the gym is average and full of mosquitos, good food at the lobby and wifi is strong. The check out time is 11:00am which is crazy, no hotel in the world does that, I am a Hilton Honors Gold Member and they didnt care, managed to get a checkout at 12:00pm which was a real struggle! No Hilton Standard, bad and arrogant service, poor location, could have been much much much better, but they don't seem to care!