Stayed at the Hotel Jane for 3 nights in March and was extremely happy with the time spent there. The hotel staff were all incredibly polite and helpful, they gave us a free map and directions on arrival. The room was compact and clean, it was cleaned daily and toilet rolls, towels and soaps were freshly replenished every day. I was pleasantly surprised to find a double bed instead of two singles pushed together. The room had an air con unit, hairdryer (don't expect a salon finish), mini fridge and an electronic safe which was helpful for storing valuables.
The hotel breakfast was light and tasty, with fresh fruit, pastries, toast, yoghurts, cereals and granola, boiled eggs, cold cuts and cheeses as well as fresh fruit juice, still and sparkling water and a selection of teas and coffees. One thing that some travellers might find quite strange at first is that you have to leave your room key at the hotel (there's a 24 hour reception) when you leave for the day. This is a great idea though as it means there's no possibility of losing your key.
The hotel is well situated for walking into the centre, we walked along the Arno every day for around 15 minutes before we reached the centre. If you want to to visit the main attractions like the Duomo and the Uffizi I recommend buying tickets in advance to avoid queues. Another tip I would give to English speaking travellers is to make an effort with your Italian, even if it's just reading off a menu in Italian rather than English, it will be appreciated by locals.