My wife and I recently spent 4 nights at the Embassy Hotel - located in a quiet street in an inner north suburb of Athens. It is quiet and clean and we had a room with a balcony at the rear overlooking some gardens. The staff are helpful and very friendly and it offers a good breakfast.
A metro station is close by (beware of pickpockets), and there are quite a few small eateries, bars and mini marts within walking distance. The hotel does not have a restaurant.
The Embassy offers a good choice if you are looking for a hotel away from the noisy Plaka and other tourist areas.
If visiting Athens again we would definitely stay there.More