Although going along the river can be quite nice, the really interesting bit is going to Les Glénans.
We go there every year, either using the vedettes de l'Odet (for booking http://www.vedettes-odet.com/ - 02 98 57 00 58) or renting a motor boat (from Ile Tudy or Loc Tudy as it is less expensive than Benodet for ex - but you need a license). Les Vedettes also start from Loc Tudy.
They propose different options, we only used the trip to St Nicolas island.
The Islands are wonderful, with cristal clear turquoise waters (they are in the middle of the ocean). Of course, water is colder than on the continent. Bring your snorkeling gear.
The very best way is to go there sailing (did that also) but you should be experienced (lots of rocks), but you can go (as with the motor boat) to beaches where nobody can!
The Glénans is world famous for its sailing school (in fact all types of wind propelled engines).
It is a paradise for sailing.
If you stay on St Nicolas, there is a board walk giving you access to several beaches.
One apex of your visit is the restaurant Les Viviers-Castric (02 98 50 68 90 - in season you must make a reservation as they limit the number of tables) - half our motivation to go there, for their simple but delicious grilled blue lobster. The rest of the food is basic and just OK. But the blue lobster is the best lobster you can eat (I am a cook), it is fished locally, and you could see your victims in the huge sea tank of the restaurant. The rest of the food is average, but you'll have trouble to find anywhere lobster at that price. As a starter, you won't be disappointed with the crab or the fish soup. Deserts are so-so.
Finally, it is windy there, in the ocean, hence bring a sweater and rain gear as the weather changes often. If you are lucky to have a sunny day - you will be in paradise.
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