We have stayed at both the Ramada and the Best Western as we have a relative at Altus AFB. The Best Western is a fairly good, although worn, hotel. The front lobby, indoor/outdoor pool and free continental breakfast are very nice. The rooms are older with each having a microwave and minifridge. Some rooms have a desk, others have a table and chairs. The bathrooms are just average, but if you're not going to spend much time in your room, the Best Western will do. Pets are allowed and there are several soda/ice machines. The hotel is right across Tamarack St. from Wal-Mart and several other stores. It is a short drive from Altus AFB, and within walking distance to Applebee's.
The Microtel Hotel is the newest hotel in Altus at Continental and Main St., but it doesn't have a pool. So, if a pool is important, the Best Western is the best hotel. Soon, though, a Hampton Inn will be opening near the Applebee's and Microtel.