Situated on the river Guadalquivir, southern Spain's largest city has been home to Carmen, Don Juan and Figaro, and its Gothic cathedral is the resting place of Columbus. Muslim and Jewish art can be seen throughout the Reales Alcazares. It's a contagiously romantic city whose celebratory ambiance pervades Seville's winding streets and spills out of the bars and tapas parlors of Santa Cruz and Plaza Alfalfa. Make sure to climb the Giralda tower for a spectacular view of the city.