According to forum posts, travelers looking for quieter stays in Santa Cruz de Tenerife have recommended the Hotel Colon Rambla. It is noted for being in a central yet residential area, making it quieter at night. This hotel offers a pool and onsite parking, making it convenient for those who might want to hire a car.

For those interested in easy access to other parts of the island, staying in La Laguna has been suggested. It is conveniently connected by tram to Santa Cruz, allowing for easy day trips to the city while enjoying a quieter evening atmosphere. La Laguna is also close to the bus terminal, facilitating travel to other areas.

Other travelers have discussed staying in smaller centers like San Andres, which provides a gateway to Anaga Park, ideal for walking and exploring. San Andres offers a more laid-back atmosphere with sufficient amenities and is well-connected by bus to Santa Cruz.

According to forum posts, there is a regular bus service available from Santa Cruz. Travelers can check bus frequencies on the TITSA website and purchase tickets directly on the bus.

Some travelers mentioned that taxis are readily available from Santa Cruz to various destinations. For instance, a taxi from Santa Cruz to Tenerife North airport might cost around €25, and the journey takes about 15-20 minutes depending on traffic.

For those looking for a unique experience, forum contributors suggest using the local tram service to visit La Laguna from Santa Cruz, which offers a scenic route showcasing historic sites and colonial architecture.