Some travelers recommended Hotel Astoria near Brignole Station for its proximity to transportation, quiet environment, and excellent services, including a reasonable parking option for those traveling by car. Another suggestion was Hotel Bristol, praised for its prime location, making it walkable to most sights and restaurants.

For those looking to stay in a central location, areas around Piazza Colombo and Brignole are favored for their accessibility to public transport and proximity to the old Medieval Quarter. The area near Piazza Principe train station was also mentioned as a convenient location, especially for those interested in exploring historical sites and museums.

Travelers have called out specific hotels like the Best Western Moderno Verdi near Brignole Station and Hotel Vittoria Orlandini near Piazza Principe for their strategic locations. These hotels are close to train stations, enhancing convenience for day trips and exploring the city.

For those traveling with children, staying near Porto Antico, which is part of the old city center, is recommended due to its safety during family-friendly hours and proximity to attractions like the Aquarium.

According to forum posts, the Airlink bus service connects Genoa Airport to Genova Sestri Ponente Aeroporto train station, with tickets priced at €1.60, which also cover a train ride to central Genoa locations. Additionally, the Volabus service offers direct routes from the airport to central train stations and main squares like Piazza de Ferrari, costing €6 or €5 if purchased online.

Travelers have highlighted that Genoa offers a comprehensive public bus system managed by AMT. Tickets are priced at €1.50 for 100 minutes of travel on buses, except for the Volabus. There are also day tickets available for €4.50, and a group day ticket for up to four people costs €9.50. These tickets include travel on regional trains within city limits.

Some posts mentioned experimental free travel on buses and other public lifts between specific hours (10 am to 4 pm and 8 pm to 10 pm). However, standard bus services require a ticket at all times, except when the metro is closed for maintenance and a replacement bus service is offered.

According to forum posts, Genoa is considered a practical base for exploring nearby destinations like Portofino, Camogli, and the Cinque Terre. Travelers have highlighted the city's good rail connections, especially from Brignole Station, which provide easy day trips to these locations.

Some travelers expressed concerns about safety at night near certain areas like the Hotel de Ville. However, areas closer to Brignole Station have been recommended for their proximity to transportation and the availability of quality hotels like the Best Western Moderno Verdi.

Travelers have called out Genoa's vibrant night scene, particularly around the old Medieval Quarter and Porto Antico area, which are accessible via the metro from Brignole Station. This makes Genoa a lively base for those who enjoy evening entertainment.

For many users, Genoa offers a blend of accessibility to tourist sites and a rich urban experience, making it a recommended base for both exploring the Ligurian coast and enjoying city life.