Citizens of the EU can drive in Agrigento with their driver licenses from home. People from other countries (such as the United States and Canada) must get an international permit from an automobile club, which usually just requires you to show a valid driver’s license from your home country. The minimum driving age in Italy is 18. Agrigento traffic tends to be light in comparison to the larger Sicilian cities (Palermo, Catania and Messina), but motorists tend to drive more aggressively than what most North Americans are accustomed to. Cars are a good way for getting about Agrigento, especially if you want to see some of the inland countryside. Agrigento is on the highway SS189 that connects to Palermo or SS115, which connects to Trapani and several other nearby towns.

Travel between cities or around the coast is most efficient by train (assuming no strikes). TrenItalia is the national train service, with services to the Italian mainland once or twice a day via a ferry across the Messina strait. There are also buses that run between cities on Sicily, with the main companies being Interbus and Azienda Siciliana Trasporti (AST). For inner-city travel, bars, newsstands and other small shops often sell tickets for buses. Make sure you have a valid ticket when you board or you will be subject to a heavy fine. Bus and train conductors get commissions for giving fines, so they are quite aggressive about their job.