If you plan to fly into Molokai, there are two airports to choose from—Hoolehua and Kalaupapa. Most flights arrive at Hoolehua, commonly referred to as the Molokai airport.

Island Air offers flights from Honolulu and flights from Maui every day via twin-engine jet prop planes. Other options are Go! Express, which offers daily single engine jet prop Cessna Caravan small-plane flights from Honolulu, and Pacific Wings, which flies from Honolulu to Molokai several times a day also using a single engine jet prop Cessna Caravan. Molokai Air Shuttle no longer flies.

The Molokai airport is located about five miles from Kaunakakai. You can easily rent a car right at the airport; there are four agencies to choose from including Budget and Dollar, or you can also get a taxi.

You can also take a ferry ride from Lahaina Harbor in Maui to Kaunakakai Wharf in Molokai. The Molokai Princess, a 100-foot yacht that holds about 150 passengers, makes the 90-minute trip every day. There are also package deals available, such as cruise & drive deals, where the overall price includes round-trip ferry passage plus a rental car. Other deals include the ferry and a guided tour in an air-conditioned van.