There are many vibrant nightlife scenes, mostly beach-inspired, in Clearwater and in the nearby areas.

In Clearwater Beach, Shepherd's Beach Resort is definitely party central. The Wave Club is on the first floor of the main hotel building, is indoors and is very loud. It had a real modern neon light kind of thing going inside but renovations may change the decor as well.  The Tiki Bar is outside of the hotel on the beach. Actually, there is a short pier on the beach where the live band sets up. The tiki bar faces it in between the restaurant and the pool.  Every weekend, boats pull up and anchor off of the beach and the boaters come in for dinner and/or drinks or just to chill out and hear the band.  The crowd on the weekends is young (20s). Beware of long drinking weekends like Memorial Day weekend or Labor Day weekend when crowds can be standing room only. (If you are staying at Shepherd's Beach, you may do well to ask for a room far away from the action – eventually you will want to sleep).

Frenchy's Rockaway Grill, the largest of the Frenchy's establishments in Clearwater Beach, opens right onto the Gulf sand and is a great place to hear live music. Also on the beach and across the parking lot from Frenchy's is the Palm Pavilion Beachside Grill and Bar. With live jams and the ocean breeze echoing in their ears, patrons often take to dancing this relaxed beachfront venue.

The Brown Boxer Pub & Grille is a new sports-themed pub has quickly become a favorite of locals and visitors. The pool table is a big draw, and the pub has live music several nights of the week. Clearwater Wine Bar & Bistro is something a little bit different from what you normally see in the area. Think fewer daiquiris and bikinis and more wines and craft beers. The menu features more than 150 wines, craft brews and Mediterranean and Mexican fare.