The borough of West Chester is about 25 miles (40 km) from downtown Philadelphia, so its public transportation service is run by SEPTA (Southeast Pennsylvania Transportation Authority), which serves most Philadelphia suburbs. SEPTA provides bus services within West Chester, as well as commuter rail trains from West Chester to Philadelphia. Fares are about $2 for travel within one zone, with additional charges for travel between towns or into Philadelphia. Weekly or monthly passes with unlimited travel are also available.

The West Chester Transportation Center is the main terminal for the borough’s public transport system. The recently opened bus center can be found on Market Street, across from the Chester County Justice Center. There are only a few lines running presently, connecting the center of the borough with the Exton Square Mall, the Paoli Train Station, West Chester University, and other important places in the region.

The streets of West Chester are mostly in a grid pattern, so driving around is easy. There are also several large metered or hourly parking lots around town, so parking is usually not a problem. For car rentals, there is a Hertz agency office on Market Street, Dollar on Autopark Boulevard and Avis on West Chester Pike.